Comparison of the Palatability of a New Flavoured Drontal® Plus Tablet (Drontal® Plus Treat 10 kg) and Milbemax® Chewable Tablets When Presented to Privately Owned Dogs

نویسندگان

  • Gabriele Petry
  • Josephus Fourie
  • Sonja Wolken
چکیده

There is an increased need for highly palatable oral dosage forms for dogs and cats, especially in the case of regular or chronic medications. To meet this need of easy application, the original Drontal® Plus tablet, a broad-spectrum anthelminthic, was optimized using a novel formula. A field study was conducted to evaluate the palatability of this new Drontal® Plus formula in comparison to a positive control product (Milbemax® Chewable Tablets) with a well-known high palatability. The study also aimed to get a palatability claim which necessitates the conduct of appropriate studies. 150 privately owned dogs of 38 pure or mixed breeds, six months to twelve years old, and with a weight range of 5 to 50 kg were included. The study was based on a cross-over design, and a standardized acceptance test was used to evaluate and compare the palatability of the two medications. In this study 88% of dogs voluntarily consumed Drontal® Plus Treat 10 kg, and 86.7% accepted Milbemax® Chewable Tablets. In the majority of cases (IVP: 98%, CP: 95%) the tablets were taken directly from the owner’s hand. The new Drontal® Plus tablet showed a high palatability compared to the Milbemax® Chewable Tablets when used in a household study design with privately owned dogs.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Development and evaluation of orally disintegrating tablets of Pramipexole using full factorial design

Pramipexole is the mostly prescribed drug in patients with Parkinson disease. The incidence of Parkinson disease is related to aging and mostly developed in elderly people with difficulty in swallowing or dysphagia. In the current study we aimed to develop an orally fast disintegrating tablet (ODT) of pramipexole as a preferable alternative in geriatric patients. Hence, the fast disintegration ...

متن کامل

Extraction of Zn, Mn and Co from Zn-Mn-Co-Cd-Ni containing solution using D2EHPA, CYANEX® 272 and CYANEX® 302

Effects of pH, D2EHPA, Cyanex® 302 and Cyanex® 272 on extractions of zinc, manganese and cobalt from a Zn-Mn-Co-Cd-Ni containing solution was comprehensively investigated at the room temperature. The addition of Cyanex® 302 indicated a left-shifting-effect on the extraction curve of zinc, a right-shifting-effect on the extraction curve of manganese and no effect on the extraction of cobalt. The...

متن کامل

Low-Pressure Radiofrequency Cold Plasma for Disinfection of Gutta-Percha Cones

Background and Aim: Different methods have been proposed for rapid disinfection of gutta-percha (GP) cones. This study aimed to assess the efficacy of low-pressure radiofrequency cold plasma (LRFCP) in disinfection of GP cones compared to three chemical disinfectants. Materials and Methods: Seventy GP cones were allocated to seven groups of 10 each. All samples were initially sterilized with e...

متن کامل

Effects of commercial synbiotic Biomin®IMBO on growth performance, some biochemical parameters and skin mucosal immunity in crucian carp (Carassius carassius)

In this study, the effects of commercial synbiotic Biomin®IMBO at  1 and 5 g kg-1 incorporated in control diet on growth performance, some biochemical parameters and skin mucosal immunity was investigated in crucian carp (Carassius carassius). Fish (8.03 ±0.36 g) were randomly distributed among nine aquaria with 12 fish per each aquarium and fed different diets for 45 days. With 5 g kg-1synbiot...

متن کامل

Comparison of Efficacy and Safety of Two Different Enoxaparin Products in Prevention of Venous Thromboembolism Following Major Obstetric-gynecological Surgeries: An Open-label Randomized Clinical Trial

Venous thromboembolism (VTE) occurs in about 5 percent of patients undergoing major abdominal surgeries. Prophylaxis of VTE is recommended using unfractionated heparin (UF) or low molecular weight heparin (LMWH) in high-risk patients. In spite of advantages and confirmed cost-effectiveness of LMWH, high costs of enoxaparin branded preparations limit its use. We aimed to compare the efficacy and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014